上海普迈生物科技有限公司是一家集研发、销售与技术服务为一体的高新技术企业,公司专业经营生命科学领域的研究试剂、仪器和实验室消耗品,并提供生命科学前沿研究技术服务,致力于打造一个专业的一站式购物和服务平台,其产品包括微生物学、分子生物学、细胞生物学、免疫学、蛋白研究、信号传导和神经科学等领域。 公司产品种类齐全,可提供在各个领域的品牌产品,如:Jena Bioscience、Omicron、Eurogentec、Leinco technologies、Smartox、Osenses等试剂与
耗材品牌 点击展示更多内容 Metkinen Chemistry代理,Metkinen Chemistry中国代理,Metkinen Chemistry上海代理,Metkinen Chemistry北京代理,Metkinen Chemistry广州代理,Metkinen Chemistry代理,Metkinen Chemistry Metkinen Chemistry代理,Metkinen Chemistry中国代理,Metkinen Chemistry上海代理,Metkinen Chemistry北京代理,Metkinen Chemistry广州代理,Metkinen Chemistry代理,Metkinen Chemistry2 -Deoxy-2 -fluoronucleosides DerivativesSynthetic RNA oligonucleotides, incorporating 2 -Deoxy-2 -fluoro-nucleosides (2 -F-RNA) find constantly increasing applications in research and new drug development. Among important areas of their application are such as design and synthesis of efficient and stable siRNAs, aptamers, anti-microRNAs (Antagomirs) as well as general use for affinity purification of RNA-binding proteins.Today Metkinen Chemistry offers more than 99% pure purine 2 -fluoronucleosides, prepared by bioconversion of synthetic 2 -F-uridine, using evolved recombinant E.coli strains. These strains, in turn are grown on the media, incorporation only ingredients, derived from yeast and vegetable. That means that in the production process no secondary reagents of animal source (either BSE certified or non- BSE certified) are employed at any stage of 2 -F- A and G preparation. Hence, we guarantee the complete absence of ANY BSE/TSE risk, associated with our 2 -F-nucleosides and derivatives.In addition to purine 2 -F-nucleosides, we offer a full set of 2 -F-nucleoside CE-phosphoramidites for chemical synthesis and a full set of 2 -F-nucleoside 5 -triphosphates for enzymatic preparation of 2 -F-RNA. Our latest addition to series of 2 -fluoronucleoside derivatives 2 -F-nucleoside bound solid supports for 2 -F-RNA oligosynthesis, complements the range of these compounds and opens up a full spectrum of 2 -F-RNA applications. 2 -Fluoro modifications consistently provided increased target binding affinity, endonuclease stability, and, importantly, reduced immune response. In addition, it is the only modification compared to other carbohydrate modifications, including locked nucleic acid, or LNA, that preserves RISC activity when used in both sense and antisense strands.2 -Deoxy-2 -fluoroguanosine2 -Deoxy-2 -fluoroadenosine2 -Deoxy-2 -fluoroguanosine-3 -CE-phosphoramidite2 -Deoxy-2 -fluoroadenosine-3 -CE-phosphoramidite2 -Deoxy-2 -fluorouridine-3 -CE-phosphoramidite2 -Deoxy-2 -fluorocytidine-3 -CE-phosphoramidite2 -Deoxy-2 -fluoroarabinonucleosides (FANA) Derivatives2 -Fluoroarabinooligonucleotides (FANA) can be used as antisense oligonucleotides, siRNA and aptamers. Today Metkinen Chemistry offers synthetically synthesized pyrimidine 2 -fluoroarabinonucleosides as well as purine 2 - fluoroarabinonucleosides, prepared by bioconversion of synthetic 2 -F-arabinouridine, employing propriarory evolved recombinant E.coli strains. We guarantee the complete absence of ANY BSE/TSE risk, associated with our 2 -F- fluoroarabinonucleosides. Metkinen Chemistry offers a full set of 2 -F-nucleoside CE-phosphoramidites for the chemical synthesis and a full set of 2 -F-nucleoside 5 -triphosphates for enzymatic preparation of FANA.9-(2-Deoxy-2-fluoro- -D-arabinofuranosyl)adenine (2 -FANA-A)9-(2-Deoxy-2-fluoro- -D-arabinofuranosyl)-2,6-diaminopurine (FANA-DAP)9-(2-Deoxy-2-fluoro- -D-arabinofuranosyl)guanine (2 -FANA-G)9-(2-Deoxy-2-fluoro- -D-arabinofuranosyl)hypoxantine (2 -FANA-I)1-(2-Deoxy-2-fluoro- -D-arabinofuranosyl)cytosine (2 -FANA-C)1-(2-Deoxy-2-fluoro- -D-arabinofuranosyl)uracil (2 -FANA-U)9-(2-Deoxy-2-fluoro- -D-arabinofuranosyl)-6-thioguanine (FANA-thioG)2 -Deoxy-2 -fluoroarabinoadenosine-3 -CE-phosphoramidite2 -Deoxy-2 -fluoroarabinoguanosine-3 -CE-phosphoramidite2 -Deoxy-2 -fluoroarabinouridine-3 -CE-phosphoramidite2 -Deoxy-2 -fluoroarabinocytidine-3 -CE-phosphoramidite上海普迈生物致力于提供高质量的产品和服务组织形态学研究与竞争力的产品欢迎下载下面的资料以了解此产品的相关信息!预询产品订购信息产品和服务,有相关产品的问题请直接期货每周下午5点前发定单,正常到上海时间为3-4周现市区2天内送到,外地以快递为准敬请关注!: :www.pumaibio.com:pumaibio:(直接客户)(经销商)促销etonbio、polysciences、Mattek、trevigen、Chromogenix、cyguns、IrvineScientific、Innovative Cell Technologies、enzo、novus、immunochemistry、eylabs、Polyplus、NIBSC、ALZET、hitobiotec、sutter instrument、mirus、StressMarq、
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